Seleccione una sola respuesta salvo que se indique lo contrario.
Especimen
Tumor
Hallazgos adicionales
Estudios especiales
Comentarios
Hecho por Josselyn Hernandez Copyright
Table 1. Nuclear Grade of Ductal Carcinoma In Situ
| Feature | Grade I (Low) |
Grade II (Intermediate) |
Grade III (High) |
|---|---|---|---|
| Pleomorphism | Monotonous (monomorphic) | Intermediate | Markedly pleomorphic |
| Size | 1.5 to 2 x the size of a normal RBC or a normal duct epithelial cell nucleus | Intermediate | >2.5 x the size of a normal RBC or a normal duct epithelial cell nucleus |
| Chromatin | Usually diffuse, finely dispersed chromatin | Intermediate | Usually vesicular with irregular chromatin distribution |
| Nucleoli | Only occasional | Prominent, often multiple | |
| Mitoses | Only occasional | Intermediate | May be frequent |
| Orientation | Polarized toward luminal spaces | Intermediate | Usually not polarized toward the luminal space |
Definition: RBC, red blood cell.
Distinguishing DCIS from LCIS
| Feature | LCIS | DCIS |
|---|---|---|
| Loss of cohesion | Present | Absent |
| Intracytoplasmic vacuoles | More common | Less common |
| Pagetoid ductal involvement | More common | Less common |
| Microacini | Absent | Present |